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Sheng Yang Selected Research

8- dioxa- 11- azadispiro(2.0.4.3)undec- 11- yl)ethoxy)- 7- methoxy- 4- quinazolinamine N-(3-chloro-4-fluorophenyl)-6-(2-(5

1/2019Safety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer: results of a phase Ib trial.
2/2014Development and validation of a UPLC-MS/MS assay for the quantification of simotinib in human plasma.

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Sheng Yang Research Topics

Disease

85Neoplasms (Cancer)
04/2022 - 10/2002
22Infections
12/2022 - 02/2005
20Stomach Neoplasms (Stomach Cancer)
01/2022 - 07/2011
18Lung Neoplasms (Lung Cancer)
03/2021 - 03/2003
17Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2020 - 01/2012
14Lymphoma (Lymphomas)
09/2021 - 01/2012
12Adenocarcinoma of Lung
03/2021 - 10/2013
12Carcinogenesis
01/2021 - 01/2006
10Neutropenia
11/2020 - 04/2006
9Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
05/2022 - 05/2012
9Disease Progression
04/2022 - 11/2012
9Neoplasm Metastasis (Metastasis)
03/2020 - 01/2012
8Breast Neoplasms (Breast Cancer)
01/2016 - 10/2011
7Nasopharyngeal Carcinoma
01/2020 - 02/2013
6Non-Hodgkin Lymphoma (Lymphosarcoma)
10/2017 - 09/2005
5Hypertension (High Blood Pressure)
02/2022 - 05/2013
5Stroke (Strokes)
01/2022 - 10/2002
5Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2020 - 06/2009
5Brain Neoplasms (Brain Tumor)
03/2020 - 09/2015
5Thrombocytopenia (Thrombopenia)
01/2018 - 10/2009
4Type 2 Diabetes Mellitus (MODY)
06/2022 - 04/2013
4Insulin Resistance
06/2022 - 05/2012
4Fatigue
11/2021 - 09/2005
4Anemia
07/2021 - 02/2016
4Adenocarcinoma
10/2019 - 10/2013
4Carcinoma (Carcinomatosis)
05/2018 - 11/2017
4Lymphatic Metastasis
10/2017 - 01/2012
4Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
02/2017 - 03/2013
4B-Cell Lymphoma (Lymphoma, B Cell)
09/2015 - 08/2009
3Acquired Immunodeficiency Syndrome (AIDS)
12/2022 - 03/2004
3T-Cell Lymphoma (Lymphoma, T Cell)
07/2022 - 01/2018
3Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma)
07/2022 - 11/2012
3Diabetes Mellitus
02/2022 - 12/2014
3COVID-19
01/2022 - 01/2020
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2021 - 01/2017
3Osteoporosis
01/2021 - 08/2016
3Aortic Dissection
08/2020 - 06/2010
3Colonic Neoplasms (Colon Cancer)
05/2020 - 03/2016
3Inflammation (Inflammations)
01/2020 - 02/2013
3Melanoma (Melanoma, Malignant)
01/2020 - 01/2018
3Colorectal Neoplasms (Colorectal Cancer)
11/2017 - 09/2011
3Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
06/2016 - 05/2012
3Body Weight (Weight, Body)
11/2013 - 05/2012
3Cognitive Dysfunction
01/2012 - 05/2006
3Pain (Aches)
04/2006 - 01/2005
2Fibrosis (Cirrhosis)
02/2022 - 01/2022
2Liver Neoplasms (Liver Cancer)
01/2022 - 01/2019
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2022 - 04/2013
2Ischemic Stroke
01/2022 - 10/2019
2Heart Failure
07/2021 - 08/2007

Drug/Important Bio-Agent (IBA)

30Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2012
25Proteins (Proteins, Gene)FDA Link
03/2022 - 10/2002
21MicroRNAs (MicroRNA)IBA
12/2022 - 02/2013
13Long Noncoding RNAIBA
01/2021 - 01/2014
11Rituximab (Mabthera)FDA Link
05/2022 - 08/2009
11Biological ProductsIBA
01/2022 - 01/2012
10Pharmaceutical PreparationsIBA
12/2022 - 04/2014
10RNA (Ribonucleic Acid)IBA
01/2022 - 05/2013
9ErbB Receptors (EGF Receptor)IBA
01/2019 - 09/2011
8Messenger RNA (mRNA)IBA
12/2022 - 10/2014
8Cisplatin (Platino)FDA LinkGeneric
01/2022 - 09/2015
8GemcitabineFDA Link
11/2019 - 03/2013
7PlatinumIBA
01/2020 - 10/2013
7Guanosine Diphosphate (GDP)IBA
11/2019 - 03/2013
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2016 - 07/2011
6Dexamethasone (Maxidex)FDA LinkGeneric
11/2019 - 07/2015
6Tyrosine Kinase InhibitorsIBA
01/2019 - 10/2013
5Transcription Factors (Transcription Factor)IBA
01/2022 - 01/2018
5Therapeutic UsesIBA
01/2022 - 03/2003
5DNA (Deoxyribonucleic Acid)IBA
10/2019 - 08/2009
4Monoclonal AntibodiesIBA
02/2022 - 09/2011
4EnzymesIBA
02/2022 - 01/2020
4N-methyladenosineIBA
01/2021 - 01/2020
4CytokinesIBA
01/2020 - 10/2015
4L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2020 - 08/2014
4icotinibIBA
12/2017 - 01/2016
4SurvivinIBA
12/2014 - 01/2012
4Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2012 - 04/2006
3artenimol (dihydroartemisinin)IBA
01/2022 - 01/2019
3Focal Adhesion Protein-Tyrosine KinasesIBA
05/2021 - 08/2016
36-methyladenineIBA
01/2021 - 01/2020
3apatinibIBA
03/2020 - 01/2017
3Metformin (Glucophage)FDA LinkGeneric
01/2020 - 05/2012
3InterleukinsIBA
01/2020 - 02/2013
3Interleukin-6 (Interleukin 6)IBA
01/2020 - 02/2013
3Pemetrexed (MTA)FDA Link
10/2019 - 10/2013
3Carboplatin (JM8)FDA LinkGeneric
03/2016 - 04/2006
3IfosfamideFDA LinkGeneric
09/2015 - 07/2015
3pegylated granulocyte colony-stimulating factorIBA
12/2006 - 04/2006
2Anaplastic Lymphoma KinaseIBA
07/2022 - 02/2015
2Phosphatidylinositols (Phosphatidylinositol)IBA
06/2022 - 10/2016
2AnthracyclinesIBA
04/2022 - 11/2019
2toripalimabIBA
02/2022 - 01/2020
2Immunoglobulin G (IgG)IBA
02/2022 - 01/2020

Therapy/Procedure

43Drug Therapy (Chemotherapy)
04/2022 - 04/2006
33Therapeutics
12/2022 - 03/2003
5Radiotherapy
01/2021 - 09/2015
4Stem Cell Transplantation
04/2022 - 09/2005
4Transplantation
01/2021 - 03/2005
4Hematopoietic Stem Cell Transplantation
10/2017 - 06/2009